I read the same about GDF11, I am 28 years old and have been diagnosed with Leukoaraiosis, which doctors say is untreatable. However, after reading about GDF11 I feel that this might be the cure I a looking for. If the experiment as done with mice can be done on humans. I would readily participate in it. Also, I had a question about obtaining GDF11 from an aborted fetus? Is it possible to extract is from the fetus before it is aborted? Also, If I get blood from a child, without causing any harm to that child. Is it possible to get GDF11 from it?
I had been looking for ways to get young blood to separate out the plasma ans use it on myself, but I have doubts related to using it, as to getting a new infection from that blood.

Hi,
you do not need blood to contain GDF11. The human GDF11 is a so called antibody which is already produced in labs (by E.coli) and can be bought in several biosource internet shops. You just have to give them some evidence that you only use this for research.

You can also bye the kid to test the GDF11 blood level. (it is a bit expensive) For my understanding, you only need to know the GDF11 level of an 18 Year old of your weight and you can level up your own GDF11 by injecting the remaining substance.

As shown in mice, your stem cells in several tissues may become younger, but I don't see how this relates to your disease.

Hi Doc Kelley,

Thanks for the link. I saw the product but it seems to be quite expensive to give it a try. By the way, do you know any place where I can register for human trial for it (if it is possible). I did consult regarding this with my current doctor but it seems that he hasn't heard about it.
I will be looking here in India as well at NIMHANS.

Thanks,
pkapoor

There's a human trial beginning October, and the article noted that finding 'human volunteers' was not very difficult. It's focus will be aimed at Alzheimer's research. This should be interesting. Here's the link.

http://www.alzheimers.net/9-17-14-blood-injections-alzheimers

-Justin

GDF11 is a protein hormone, and as such it would not be easy to produce currently at levels needed for therapy and ecnonomically. That being said, insulin is also a protein hormone which is affordable for diabetics, so it is doable using recominbinant technology and probably only months of development costs with the right financial and laboratory expertise and backing. Unfortunately, this is not usually the way things happen with similar protein based drugs (like Herceptin) for example. Usually pharmaceutical companies claim they invented the wheel (when it was really open source and tax payer funded science), run the last leg of the mile, and claim patent rights. Since protein drugs are actually slighly more difficult to produce and purify than small molecule drugs and even the later are marked up by thousands of percents, you can imagine if you let the drug companies get a hold of patent rights for GDF11 what will be the story. Bottom line is there is no reason for GDF11 to be any more expensive than insulin, but it probably will be unless you call your Congressman if things pan out for the utility of this promising new agent.

pkapoor I read the same about GDF11, I am 28 years old and have been diagnosed with Leukoaraiosis, which doctors say is untreatable. However, after reading about GDF11 I feel that this might be the cure I a looking for. If the experiment as done with mice can be done on humans. I would readily participate in it. Also, I had a question about obtaining GDF11 from an aborted fetus? Is it possible to extract is from the fetus before it is aborted? Also, If I get blood from a child, without causing any harm to that child. Is it possible to get GDF11 from it?
I had been looking for ways to get young blood to separate out the plasma ans use it on myself, but I have doubts related to using it, as to getting a new infection from that blood.

http://www.lifeextension.com/Magazine/2015/2/Block-The-Vascular-Origins-Of-Cognitive-Decline/Page-01
20mg Hydergine/day.